The technology of CimCure’s lead vaccine is published in Nature Communications (Van Beijnum et al).
The Dutch government decided to fund the Oncode-PACT consortium with 325 million euro. Oncode-PACT supports the development of cancer vaccines. Together with other partners of the consortium, CimCure will accellerate its iBoost vaccination program.
CimCure is awarded by the EU with a 2.2 million euro Eurostars project, for a consortium with partners in Switzerland and France. In this project a combination therapy will be developed of CimCure’s iBoost vaccines and CAR T cells against glioblastoma.
Financial support of 1000 k€ from HEALTH-HOLLAND to Amsterdam UMC and CimCure B.V. for the generation of an evolution proof influenza vaccine by CImCure’s iBoost technology.
We are excited to welcome professor Patrycja Nowak-Sliwinska, who was trained as a biochemist and worked at the Swiss Federal Institute of Technology (EPFL), University Hospital in Lausanne (CHUV) and VU Medical Center Amsterdam, in our Scientific Advisory Board. She received her PhD from the Jagiellonian University in Crakow, Poland, and is an expert in vascular biology and cancer.
She was awarded with the Certificate of Advanced Studies (CAS) in Management of Biotech, Medtech and Pharma Ventures and is co-inventor of CimCure’s Technology. As an ERC starting grant laureate, she joined the School of Pharmaceutical Sciences at the University of Geneva, Switzerland. Her current expertise is in the design of combination therapies for the treatment of cancer.
Roberto has been a long- time physician-scientist and his research portfolio reflects grants from the National Cancer Institute and the Department of Defense on the role of epigenetics and dietary intervention as immunomodulators.
Currently, Roberto is the Associate Dean for Cancer Research and Integrative Oncology and the Chief of Hematology and Oncology at the Jacobs School of Medicine and Biomedical Sciences (JSMBS), University at Buffalo. In addition, Roberto is the Inaugural Director of the Center for Nutritional Sciences and Cancer Therapeutics at JSMBS.
We are pleased to welcome Ada Kruisbeek as Chair of the scientific advisory board. She brings a wealth of expertise and experience in the field of immunology and cancer immunotherapy.
Ada has been a long-standing researcher at the NIH in the US before becoming Head of the Department of Immunology of the Netherlands Cancer Institute and Professor of Immunology at the Free University Amsterdam.
She founded DC-Prime and became their CEO. Currently Ada serves as an advisor to DC-Prime and various other companies and foundations.
Financial support of 1351 k€ from HEALTH-HOLLAND to Amsterdam University Medical Center and CimCure B.V. for the generation of a targeted vaccine against critical domains in the spike protein of SARS-CoV-2, to be used for current and future coronaviruses based on CimCure’s iBoost technology.
Financial support of 275 k€ from HEALTH-HOLLAND for generation of a preventive cancer vaccine. This grant supports CimCure on the proof-of-principle for using its iBoost vaccine platform for the development of a multi-targeted vaccine against the tumor vasculature.
Publication Huijbers et al. accepted by Vaccine. See Huijbers et al, 2018. This paper demonstrates the value of CimCure’s proprietary technology immuno-Boost (iBoost).
Proof of Concept grant (100 k€) of the Dutch government and the VU/VUMC TTO office. This grant supports CimCure on the demonstration of the validity of cancer prevention by vaccination against very early vascular markers of tumor angiogenesis.
Publication Wentink et al. accepted by Proceeding of the National Academy of Sciences of the USA. See Wentink et al, 2016. This report from the Angiogenesis Laboratory demonstrates the validity of CimCure’s approach of anti-angiogenic vaccination strategies.